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Target
Capsid scaffolding protein
Ligand
BDBM50288087
Substrate
n/a
Meas. Tech.
ChEBML_158781
IC50
15000±n/a nM
Citation
 Jarvest, RL; Parratt, MJ; Debouck, CM; Gorniak, JG; Jennings, LJ; Serafinowska, HT; Strickler, JE Inhibition of HSV-1 protease by benzoxazinones Bioorg Med Chem Lett 6:2463-2466 (1996)    Article 
Target
Name:
Capsid scaffolding protein
Synonyms:
Human herpesvirus 1 protease | SCAF_HHV11 | UL26
Type:
PROTEIN
Mol. Mass.:
66472.05
Organism:
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)
Description:
ChEMBL_158648
Residue:
635
Sequence:
MAADAPGDRMEEPLPDRAVPIYVAGFLALYDSGDSGELALDPDTVRAALPPDNPLPINVDHRAGCEVGRVLAVVDDPRGPFFVGLIACVQLERVLETAASAAIFERRGPPLSREERLLYLITNYLPSVSLATKRLGGEAHPDRTLFAHVALCAIGRRLGTIVTYDTGLDAAIAPFRHLSPASREGARRLAAEAELALSGRTWAPGVEALTHTLLSTAVNNMMLRDRWSLVAERRRQAGIAGHTYLQASEKFKMWGAEPVSAPARGYKNGAPESTDIPPGSIAAAPQGDRCPIVRQRGVALSPVLPPMNPVPTSGTPAPAPPGDGSYLWIPASHYNQLVAGHAAPQPQPHSAFGFPAAAGSVAYGPHGAGLSQHYPPHVAHQYPGVLFSGPSPLEAQIAALVGAIAADRQAGGQPAAGDPGVRGSGKRRRYEAGPSESYCDQDEPDADYPYYPGEARGAPRGVDSRRAARHSPGTNETITALMGAVTSLQQELAHMRARTSAPYGMYTPVAHYRPQVGEPEPTTTHPALCPPEAVYRPPPHSAPYGPPQGPASHAPTPPYAPAACPPGPPPPPCPSTQTRAPLPTEPAFPPAATGSQPEASNAEAGALVNASSAAHVDVDTARAADLFVSQMMGAR
  
Inhibitor
Name:
BDBM50288087
Synonyms:
2-Ethoxy-5-methyl-benzo[d][1,3]oxazin-4-one | CHEMBL81249
Type:
Small organic molecule
Emp. Form.:
C11H11NO3
Mol. Mass.:
205.2099
SMILES:
CCOc1nc2cccc(C)c2c(=O)o1
Structure:
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