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Target
Serine protease 1
Ligand
BDBM50288454
Substrate
n/a
Meas. Tech.
ChEBML_212504
Ki
2.1±n/a nM
Citation
 Greco, MN; Powell, ET; Hecker, LR; Andrade-Gordon, P; Kauffman, JA; Lewis, JM; Ganesh, V; Tulinsky, A; Maryanoff, BE Novel thrombin inhibitors that are based on a macrocyclic tripeptide motif Bioorg Med Chem Lett 6:2947-2952 (1996)    Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50288454
Synonyms:
CHEMBL317527 | N-[3-((5S,20R,22aR)-5-Benzyl-4,7,18,19,22-pentaoxo-docosahydro-3a,6,17,21-tetraaza-cyclopentacyclohenicosen-20-yl)-propyl]-guanidine
Type:
Small organic molecule
Emp. Form.:
C31H47N7O5
Mol. Mass.:
597.7488
SMILES:
NC(=N)NCCC[C@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)CCCCCCCCCNC(=O)C1=O
Structure:
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