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Target
Phospholipase A2 group XV
Ligand
BDBM50075320
Substrate
n/a
Meas. Tech.
ChEBML_156378
IC50
9750000±n/a nM
Citation
 Isomura, S; Haruna, M; Ito, K Design and synthesis of hapten to induce phospholipase A2-like catalytic antibody Bioorg Med Chem Lett 7:251-254 (1997)    Article 
Target
Name:
Phospholipase A2 group XV
Synonyms:
1-O-acylceramide synthase | ACS | LCAT-like lysophospholipase | LLPL | LPLA2 | LYPLA3 | Lysophospholipase 3 | Lysosomal phospholipase A2 | PAG15_HUMAN | PLA2G15
Type:
PROTEIN
Mol. Mass.:
46658.20
Organism:
Homo sapiens (Human)
Description:
ChEMBL_156378
Residue:
412
Sequence:
MGLHLRPYRVGLLPDGLLFLLLLLMLLADPALPAGRHPPVVLVPGDLGNQLEAKLDKPTVVHYLCSKKTESYFTIWLNLELLLPVIIDCWIDNIRLVYNKTSRATQFPDGVDVRVPGFGKTFSLEFLDPSKSSVGSYFHTMVESLVGWGYTRGEDVRGAPYDWRRAPNENGPYFLALREMIEEMYQLYGGPVVLVAHSMGNMYTLYFLQRQPQAWKDKYIRAFVSLGAPWGGVAKTLRVLASGDNNRIPVIGPLKIREQQRSAVSTSWLLPYNYTWSPEKVFVQTPTINYTLRDYRKFFQDIGFEDGWLMRQDTEGLVEATMPPGVQLHCLYGTGVPTPDSFYYESFPDRDPKICFGDGDGTVNLKSALQCQAWQSRQEHQVLLQELPGSEHIEMLANATTLAYLKRVLLGP
  
Inhibitor
Name:
BDBM50075320
Synonyms:
(2-{[2-(Decyl-hydroxy-phosphinoyloxy)-3-(9-methoxycarbonyl-nonyloxy)-propoxy]-hydroxy-phosphoryloxy}-ethyl)-trimethyl-ammonium | CHEMBL85557 | Ester of phospholipid
Type:
Small organic molecule
Emp. Form.:
C29H61NO10P2
Mol. Mass.:
645.7429
SMILES:
CCCCCCCCCCP(O)(=O)OC(COCCCCCCCCCC(=O)OC)COP([O-])(=O)OCC[N+](C)(C)C
Structure:
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