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Target
Serine protease 1
Ligand
BDBM50291358
Substrate
n/a
Meas. Tech.
ChEBML_212526
Ki
8650±n/a nM
Citation
 Kim, S; Hwang, SY; Kim, YK; Yun, M; Oh, YS Rational design of selective thrombin inhibitors Bioorg Med Chem Lett 7:769-774 (1997)    Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50291358
Synonyms:
4-[(S)-3-Azepan-1-yl-2-(naphthalene-2-sulfonylamino)-3-oxo-propyl]-benzamidine | CHEMBL349986
Type:
Small organic molecule
Emp. Form.:
C26H30N4O3S
Mol. Mass.:
478.606
SMILES:
NC(=N)c1ccc(C[C@H](NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCCCC2)cc1
Structure:
Search PDB for entries with ligand similarity: