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TargetEDNRB
LigandBDBM50291478
Substrate/Competitorn/a
Meas. Tech.ChEBML_63708
IC50 15600±n/a nM
Citation Raju, BOkun, IStavros, FChan, MF Search for surrogates: A study of endothelin receptor antagonist structure activity relationships Bioorg Med Chem Lett7:933-938 (1997)    Article
More Info.:Get all data from this article,  Assay Method
 
EDNRB
Name:Endothelin receptor, ET-A/ET-B
Synonyms:ENDOTHELIN B | ET-B | Endothelin receptor ET-B | Endothelin receptor non-selective type | Endothelin receptor, ET-A/ET-B
Type:Enzyme Catalytic Domain
Mol. Mass.:49664.00
Organism:Homo sapiens (Human)
Description:ENDOTHELIN B EDNRB HUMAN::P24530
Residue:442
Sequence:
MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
LKFKANDHGYDNFRSSNKYSSS
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BDBM50291478
NameBDBM50291478
Synonyms:2-p-Tolyloxymethyl-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide | CHEMBL172538
TypeSmall organic molecule
Emp. Form.C16H15BrN2O4S2
Mol. Mass.443.335
SMILESCc1noc(NS(=O)(=O)c2ccsc2COc2ccc(C)cc2)c1Br
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a