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Target
Proto-oncogene tyrosine-protein kinase Src
Ligand
BDBM50291639
Substrate
n/a
Meas. Tech.
ChEBML_202782
IC50
14000±n/a nM
Citation
 Shahripour, A; Para, KS; Plummer, MS; Lunney, EA; Holland, DR; Rubin, JR; Humblet, C; Fergus, JH; Marks, JS; Saltiel, AR; Sawyer, TK Structure-based design of novel, dipeptide ligands targeting the pp60Src SH2 domain Bioorg Med Chem Lett 7:1107-1112 (1997)    Article 
Target
Name:
Proto-oncogene tyrosine-protein kinase Src
Synonyms:
Calmodulin/Proto-oncogene tyrosine-protein kinase Src | Protein cereblon/Tyrosine-protein kinase SRC | Proto-oncogene c-Src | Proto-oncogene tyrosine-protein kinase Src (c-Src) | SRC | SRC1 | SRC_HUMAN | Tyrosine-protein kinase Src (SRC) | V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | c-Src | p60-Src | pp60c-src
Type:
Protein
Mol. Mass.:
59838.60
Organism:
Homo sapiens (Human)
Description:
P12931
Residue:
536
Sequence:
MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
  
Inhibitor
Name:
BDBM50291639
Synonyms:
4-[{2-[2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-acetyl}-(3-phenyl-propyl)-amino]-butyric acid | CHEMBL267783
Type:
Small organic molecule
Emp. Form.:
C26H34N3O9P
Mol. Mass.:
563.5366
SMILES:
CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(=O)N(CCCC(O)=O)CCCc1ccccc1
Structure:
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