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TargetMuscarinic acetylcholine receptor M2
LigandBDBM50292638
Substrate/Competitorn/a
Meas. Tech.ChEMBL_496614
IC50>10000±n/a nM
Citation Bongartz, JPBuntinx, MCoesemans, EHermans, BLommen, GVWauwe, JV Synthesis and structure-activity relationship of benzetimide derivatives as human CXCR3 antagonists. Bioorg Med Chem Lett18:5819-23 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Muscarinic acetylcholine receptor M2
Name:Muscarinic acetylcholine receptor M2 and M5
Synonyms:CHRM2 | Cholinergic, muscarinic M2 | RecName: Full=Muscarinic acetylcholine receptor M2
Type:GPCR
Mol. Mass.:51730.61
Organism:Homo sapiens (Human)
Description:P08172
Residue:466
Sequence:
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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  Blast E-value cutoff:
BDBM50292638
NameBDBM50292638
Synonyms:(+)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperidine-1-carboxamide | (+/-)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperidine-1-carboxamide | (-)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperidine-1-carboxamide | CHEMBL497799
TypeSmall organic molecule
Emp. Form.C30H34BrN3O
Mol. Mass.532.514
SMILESBrc1ccc(CN2CCC(CC2)C2(CCCN(C2)C(=O)Nc2ccccc2)c2ccccc2)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a