Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50292713
Substrate
n/a
Meas. Tech.
ChEMBL_493881 (CHEMBL944252)
Ki
27±n/a nM
Citation
 Samanta, A; Leonidas, DD; Dasgupta, S; Pathak, T; Zographos, SE; Oikonomakos, NG Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation. J Med Chem 52:932-42 (2009) [PubMed]  Article 
Target
Name:
Ribonuclease pancreatic
Synonyms:
RIB1 | RNAS1_HUMAN | RNASE1 | RNAse A | RNS1 | Ribonuclease A | Ribonuclease pancreatic
Type:
Protein
Mol. Mass.:
17653.66
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
156
Sequence:
MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTNGSRYPNCAYRTSPKERHIIVACEGSPYVPVHFDASVEDST
  
Inhibitor
Name:
BDBM50292713
Synonyms:
5'-phospho-2'-deoxyuridine 3-pyrophosphate (P'->5') adenosine 3'-phosphate | CHEMBL455775
Type:
Small organic molecule
Emp. Form.:
C19H25N7O14P2
Mol. Mass.:
637.3878
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](C[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: