Reaction Details Report a problem with these data
Target
DNA polymerase beta
Ligand
BDBM50293303
Substrate
n/a
Meas. Tech.
ChEMBL_545143 (CHEMBL1018085)
Ki
390±n/a nM
Citation
 Nakane, H; Fukushima, M; Ono, K Differential Inhibition of Reverse Transcriptase and Various DNA Polymerases by Digallic Acid and Its Derivatives J Nat Prod 53:1234-1240 (1990) [PubMed]  Article 
Target
Name:
DNA polymerase beta
Synonyms:
DNA polymerase beta (Pol β) | DPOLB_HUMAN | POLB
Type:
Protein
Mol. Mass.:
38188.76
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
  
Inhibitor
Name:
BDBM50293303
Synonyms:
CHEMBL498103 | gallic acid 5,6-dihydroxy-3-carboxyphenylester
Type:
Small organic molecule
Emp. Form.:
C14H10O9
Mol. Mass.:
322.2238
SMILES:
OC(=O)c1cc(O)c(O)c(OC(=O)c2ccc(O)c(O)c2O)c1
Structure:
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