Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50180206
Substrate
n/a
Meas. Tech.
ChEMBL_604432 (CHEMBL1070688)
Ki
0.28±n/a nM
Citation
 Choi, WJ; Lee, HW; Kim, HO; Chinn, M; Gao, ZG; Patel, A; Jacobson, KA; Moon, HR; Jung, YH; Jeong, LS Design and synthesis of N(6)-substituted-4'-thioadenosine-5'-uronamides as potent and selective human A(3) adenosine receptor agonists. Bioorg Med Chem 17:8003-11 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50180206
Synonyms:
(2S,3S,4R,5R)-5-(2-chloro-6-(methylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrothiophene-2-carboxamide | 2-chloro-N6-methyl-4'-thioadenosine-5'-methyluronamide | CHEMBL201706
Type:
Small organic molecule
Emp. Form.:
C12H15ClN6O3S
Mol. Mass.:
358.804
SMILES:
CNC(=O)[C@H]1S[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC)nc(Cl)nc12
Structure:
Search PDB for entries with ligand similarity: