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Target
Cannabinoid receptor 2
Ligand
BDBM50304914
Substrate
n/a
Meas. Tech.
ChEMBL_606628 (CHEMBL1071855)
Ki
16±n/a nM
Citation
 Sellitto, I; Le Bourdonnec, B; Worm, K; Goodman, A; Savolainen, MA; Chu, GH; Ajello, CW; Saeui, CT; Leister, LK; Cassel, JA; Dehaven, RN; Labuda, CJ; Koblish, M; Little, PJ; Brogdon, BL; Smith, SA; Dolle, RE Novel sulfamoyl benzamides as selective CB(2) agonists with improved in vitro metabolic stability. Bioorg Med Chem Lett 20:387-91 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50304914
Synonyms:
CHEMBL593166 | N-(3,4-dimethyl-5-(morpholinosulfonyl)phenyl)-2,2,3,3-tetramethylcyclopropanecarboxamide
Type:
Small organic molecule
Emp. Form.:
C20H30N2O4S
Mol. Mass.:
394.528
SMILES:
Cc1cc(NC(=O)C2C(C)(C)C2(C)C)cc(c1C)S(=O)(=O)N1CCOCC1
Structure:
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