Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50308334
Substrate
n/a
Meas. Tech.
ChEMBL_613869 (CHEMBL1067692)
EC50
420±n/a nM
Citation
 Eliahu, S; Barr, HM; Camden, J; Weisman, GA; Fischer, B A novel insulin secretagogue based on a dinucleoside polyphosphate scaffold. J Med Chem 53:2472-81 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM50308334
Synonyms:
CHEMBL591433 | Di-(2-MeS)-adenosine 5',5''-P1,P4,alpha,beta-Methylene-tetraphosphate
Type:
Small organic molecule
Emp. Form.:
C23H30N10O18P4S2
Mol. Mass.:
922.568
SMILES:
CSc1nc(N)c2ncn([C@@H]3O[C@H](COP([O-])(=O)CP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)n4cnc5c(N)nc(SC)nc45)[C@@H](O)[C@H]3O)c2n1 |r|
Structure:
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