Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50423774
Substrate
n/a
Meas. Tech.
ChEMBL_613870 (CHEMBL1067693)
EC50
2.6±n/a nM
Citation
 Eliahu, S; Barr, HM; Camden, J; Weisman, GA; Fischer, B A novel insulin secretagogue based on a dinucleoside polyphosphate scaffold. J Med Chem 53:2472-81 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM50423774
Synonyms:
CHEMBL2309024
Type:
Small organic molecule
Emp. Form.:
C11H17BN5O12P3S
Mol. Mass.:
547.078
SMILES:
[BH3-]P(=O)(OC[C@H]1O[C@H]([C@H](O)[C@H]1O)n1cnc2c(N)nc(SC)nc12)OP([O-])(=O)OP([O-])([O-])=O |r|
Structure:
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