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Target
Tyrosinase
Ligand
BDBM50241530
Substrate
n/a
Meas. Tech.
ChEMBL_608142 (CHEMBL1074831)
IC50
>500000±n/a nM
Citation
 Park, JS; Kim, DH; Lee, JK; Lee, JY; Kim, DH; Kim, HK; Lee, HJ; Kim, HC Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors. Bioorg Med Chem Lett 20:1162-4 (2010) [PubMed]  Article 
Target
Name:
Tyrosinase
Synonyms:
TYRO_MOUSE | Tyr
Type:
Protein
Mol. Mass.:
60600.74
Organism:
Mus musculus (Mouse)
Description:
n/a
Residue:
533
Sequence:
MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILLSSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIRRNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMHYYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRDAENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRNPGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADPSQSSMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGHNRDSYMVPFIPLYRNGDFFITSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLGAALVGAVIAAALSGLSSRLCLQKKKKKKQPQEERQPLLMDKDDYHSLLYQSHL
  
Inhibitor
Name:
BDBM50241530
Synonyms:
CHEMBL513024 | glycitein
Type:
Small organic molecule
Emp. Form.:
C16H12O5
Mol. Mass.:
284.2635
SMILES:
COc1cc2c(cc1O)occ(-c1ccc(O)cc1)c2=O
Structure:
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