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Target
Myeloblastin
Ligand
BDBM50310690
Substrate
n/a
Meas. Tech.
ChEMBL_621098 (CHEMBL1113182)
IC50
>50000±n/a nM
Citation
 Guay, D; Beaulieu, C; Truchon, JF; Jagadeeswar Reddy, T; Zamboni, R; Bayly, CI; Methot, N; Rubin, J; Ethier, D; David Percival, M Design and synthesis of dipeptidyl nitriles as potent, selective, and reversible inhibitors of cathepsin C. Bioorg Med Chem Lett 19:5392-6 (2009) [PubMed]  Article 
Target
Name:
Myeloblastin
Synonyms:
Leukocyte proteinase 3 | MBN | PRTN3 | PRTN3_HUMAN
Type:
PROTEIN
Mol. Mass.:
27816.30
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1463425
Residue:
256
Sequence:
MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGRP
  
Inhibitor
Name:
BDBM50310690
Synonyms:
CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano-2-phenylcyclopropyl)-3-(thiophen-2-yl)propanamide
Type:
Small organic molecule
Emp. Form.:
C17H17N3OS
Mol. Mass.:
311.401
SMILES:
N[C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r|
Structure:
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