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Target
Sialidase
Ligand
BDBM50317438
Substrate
n/a
Meas. Tech.
ChEMBL_631810 (CHEMBL1109003)
IC50
31400±n/a nM
Citation
 Nguyen, PH; Nguyen, TN; Kang, KW; Ndinteh, DT; Mbafor, JT; Kim, YR; Oh, WK Prenylated pterocarpans as bacterial neuraminidase inhibitors. Bioorg Med Chem 18:3335-44 (2010) [PubMed]  Article 
Target
Name:
Sialidase
Synonyms:
NANH_VIBCH | nanH
Type:
PROTEIN
Mol. Mass.:
85590.05
Organism:
Vibrio cholerae
Description:
ChEMBL_631810
Residue:
781
Sequence:
MRFKNVKKTALMLAMFGMATSSNAALFDYNATGDTEFDSPAKQGWMQDNTNNGSGVLTNADGMPAWLVQGIGGRAQWTYSLSTNQHAQASSFGWRMTTEMKVLSGGMITNYYANGTQRVLPIISLDSSGNLVVEFEGQTGRTVLATGTAATEYHKFELVFLPGSNPSASFYFDGKLIRDNIQPTASKQNMIVWGNGSSNTDGVAAYRDIKFEIQGDVIFRGPDRIPSIVASSVTPGVVTAFAEKRVGGGDPGALSNTNDIITRTSRDGGITWDTELNLTEQINVSDEFDFSDPRPIYDPSSNTVLVSYARWPTDAAQNGDRIKPWMPNGIFYSVYDVASGNWQAPIDVTDQVKERSFQIAGWGGSELYRRNTSLNSQQDWQSNAKIRIVDGAANQIQVADGSRKYVVTLSIDESGGLVANLNGVSAPIILQSEHAKVHSFHDYELQYSALNHTTTLFVDGQQITTWAGEVSQENNIQFGNADAQIDGRLHVQKIVLTQQGHNLVEFDAFYLAQQTPEVEKDLEKLGWTKIKTGNTMSLYGNASVNPGPGHGITLTRQQNISGSQNGRLIYPAIVLDRFFLNVMSIYSDDGGSNWQTGSTLPIPFRWKSSSILETLEPSEADMVELQNGDLLLTARLDFNQIVNGVNYSPRQQFLSKDGGITWSLLEANNANVFSNISTGTVDASITRFEQSDGSHFLLFTNPQGNPAGTNGRQNLGLWFSFDEGVTWKGPIQLVNGASAYSDIYQLDSENAIVIVETDNSNMRILRMPITLLKQKLTLSQN
  
Inhibitor
Name:
BDBM50317438
Synonyms:
Abyssinone I | CHEMBL448350 | phaseollin
Type:
Small organic molecule
Emp. Form.:
C20H18O4
Mol. Mass.:
322.3545
SMILES:
CC1(C)Oc2ccc3[C@@H]4COc5cc(O)ccc5[C@@H]4Oc3c2C=C1 |r,c:26|
Structure:
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