Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBeta-2 adrenergic receptor and beta-3 adrenergic receptor
LigandBDBM25771
Substrate/Competitorn/a
Meas. Tech.ChEMBL_632379
Ki 0.39±n/a nM
Citation Baur, FBeattie, DBeer, DBentley, DBradley, MBruce, ICharlton, SJCuenoud, BErnst, RFairhurst, RAFaller, BFarr, DKeller, TFozard, JRFullerton, JGarman, SHatto, JHayden, CHe, HHowes, CJanus, DJiang, ZLewis, CLoeuillet-Ritzler, FMoser, HReilly, JSteward, ASykes, DTedaldi, LTrifilieff, ATweed, MWatson, SWissler, EWyss, D The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist. J Med Chem53:3675-84 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM25771
NameBDBM25771
Synonyms:1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]-2-methylol-phenol | 4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol | Aeromax | Salmeterol | Serevent | salmeterol xinafoate
TypeSmall organic molecule
Emp. Form.C25H37NO4
Mol. Mass.415.5656
SMILESOCc1cc(ccc1O)C(O)CNCCCCCCOCCCCc1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a