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TargetAdrenergic beta-2 receptor (beta2)
LigandBDBM50318986
Substrate/Competitorn/a
Meas. Tech.ChEMBL_635468
Ki 0.200000±n/a nM
Citation Tasler, SBaumgartner, RAschenbrenner, AAmmendola, AWolf, KWieber, TSchachtner, JBlisse, MQuotschalla, UNey, P A vHTS approach for the identification of beta-adrenoceptor ligands. Bioorg Med Chem Lett20:3399-404 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adrenergic beta-2 receptor (beta2)
Name:Adrenergic beta-2 receptor (beta2)
Synonyms:ADRB2 | ADRB2R | ADRB2R, B2AR | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:n/a
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50318986
NameBDBM50318986
Synonyms:1-(9H-carbazol-4-yloxy)-3-(4-(4-methoxybenzyl)piperidin-1-yl)propan-2-ol | CHEMBL1082500
TypeSmall organic molecule
Emp. Form.C28H32N2O3
Mol. Mass.444.5653
SMILESCOc1ccc(CC2CCN(CC(O)COc3cccc4[nH]c5ccccc5c34)CC2)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a