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Target
Somatostatin receptor type 5
Ligand
BDBM50322979
Substrate
n/a
Meas. Tech.
ChEMBL_643481 (CHEMBL1212345)
EC50
>1000±n/a nM
Citation
 Alker, A; Binggeli, A; Christ, AD; Green, L; Maerki, HP; Martin, RE; Mohr, P Piperidinyl-nicotinamides as potent and selective somatostatin receptor subtype 5 antagonists. Bioorg Med Chem Lett 20:4521-5 (2010) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 5
Synonyms:
SOMATOSTATIN SST5 | SS-5-R | SS5-R | SS5R | SSR5_HUMAN | SSTR5 | Somatostatin receptor type 5 (SSTR5)
Type:
Enzyme
Mol. Mass.:
39218.02
Organism:
Homo sapiens (Human)
Description:
P35346
Residue:
364
Sequence:
MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL
  
Inhibitor
Name:
BDBM50322979
Synonyms:
CHEMBL1210209 | N-(1-((2,6-diethoxy-4'-fluorobiphenyl-4-yl)methyl)piperidin-4-yl)-6-(methylamino)nicotinamide
Type:
Small organic molecule
Emp. Form.:
C29H35FN4O3
Mol. Mass.:
506.6116
SMILES:
CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(NC)nc2)cc(OCC)c1-c1ccc(F)cc1
Structure:
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