Reaction Details Report a problem with these data
Target
Carbonic anhydrase 13
Ligand
BDBM50323751
Substrate
n/a
Meas. Tech.
ChEMBL_646963 (CHEMBL1217104)
Ki
52000±n/a nM
Citation
 Carta, F; Temperini, C; Innocenti, A; Scozzafava, A; Kaila, K; Supuran, CT Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. J Med Chem 53:5511-22 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 13
Synonyms:
CA-XIII | CAH13_MOUSE | Ca13 | Car13 | Carbonate dehydratase XIII | Carbonic anhydrase 13 | Carbonic anhydrase XIII
Type:
Enzyme
Mol. Mass.:
29522.80
Organism:
Mus musculus (mouse)
Description:
Murine cloned isozyme
Residue:
262
Sequence:
MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKIISNSGHSFNVDFDDTEDKSVLRGGPLTGNYRLRQFHLHWGSADDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAAFLLSNHRPPQPLKGRRVRASFY
  
Inhibitor
Name:
BDBM50323751
Synonyms:
CHEMBL609 | N,N'-BIS(2-AMINOETHYL)-1,2-ETHANEDIAMINE | N,N'-Bis-(2-amino-ethyl)-ethane-1,2-diamine | Syprine | TRIENTINE | triethylenetetramine
Type:
Small organic molecule
Emp. Form.:
C6H18N4
Mol. Mass.:
146.2339
SMILES:
NCCNCCNCCN
Structure:
Search PDB for entries with ligand similarity: