Target
Carbonic anhydrase 3
Ligand
BDBM79403
Substrate
n/a
Meas. Tech.
ChEMBL_646955
Ki
167000±n/a nM
Citation
 Carta, FTemperini, CInnocenti, AScozzafava, AKaila, KSupuran, CT Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. J Med Chem 53:5511-22 (2010) [PubMed]  Article
Target
Name:
Carbonic anhydrase 3
Synonyms:
CA-III | Carbonate dehydratase III | Carbonic Anhydrase III | Carbonic anhydrase | Carbonic anhydrase 3 (CA III) | Carbonic anhydrase III (CA III)
Type:
Enzyme
Mol. Mass.:
29562.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
260
Sequence:
MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRVVRASFK
  
Inhibitor
Name:
BDBM79403
Synonyms:
3-aminopropyl-[4-(3-aminopropylamino)butyl]amine;hydrochloride | CHEMBL23194 | MLS002472980 | N,N''-bis(3-aminopropyl)butane-1,4-diamine;hydrochloride | N,N''-bis(3-azanylpropyl)butane-1,4-diamine;hydrochloride | N,N'-bis(3-aminopropyl)butane-1,4-diamine | SMR001397086 | Spermine | cid_5351186 | spermidine 3HCl
Type:
Small organic molecule
Emp. Form.:
C10H26N4
Mol. Mass.:
202.3402
SMILES:
NCCCNCCCCNCCCN
Structure:
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