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Target
D(2) dopamine receptor
Ligand
BDBM50327863
Substrate
n/a
Meas. Tech.
ChEMBL_664951 (CHEMBL1259908)
Ki
615±n/a nM
Citation
 Xu, R; Hong, J; Morse, CL; Pike, VW Synthesis, structure-affinity relationships, and radiolabeling of selective high-affinity 5-HT4 receptor ligands as prospective imaging probes for positron emission tomography. J Med Chem 53:7035-47 (2010) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50327863
Synonyms:
(1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate | CHEMBL1258671
Type:
Small organic molecule
Emp. Form.:
C19H27FN2O4
Mol. Mass.:
366.4271
SMILES:
CCCCN1CCC(COC(=O)c2cc(F)c(N)c3OCCOc23)CC1
Structure:
Search PDB for entries with ligand similarity: