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Target
Stearoyl-CoA desaturase 5
Ligand
BDBM50329986
Substrate
n/a
Meas. Tech.
ChEMBL_676022 (CHEMBL1272960)
IC50
>20000±n/a nM
Citation
 Powell, DA; Ramtohul, Y; Lebrun, ME; Oballa, R; Bhat, S; Falgueyret, JP; Guiral, S; Huang, Z; Skorey, K; Tawa, P; Zhang, L 2-Aryl benzimidazoles: human SCD1-specific stearoyl coenzyme-A desaturase inhibitors. Bioorg Med Chem Lett 20:6366-9 (2010) [PubMed]  Article 
Target
Name:
Stearoyl-CoA desaturase 5
Synonyms:
ACOD4 | Acyl-CoA-desaturase 4 | HSCD5 | SCD2 | SCD4 | SCD5 | SCD5_HUMAN | Stearoyl-CoA 9-desaturase
Type:
PROTEIN
Mol. Mass.:
37630.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_805311
Residue:
330
Sequence:
MPGPATDAGKIPFCDAKEEIRAGLESSEGGGGPERPGARGQRQNIVWRNVVLMSLLHLGAVYSLVLIPKAKPLTLLWAYFCFLLAALGVTAGAHRLWSHRSYRAKLPLRIFLAVANSMAFQNDIFEWSRDHRAHHKYSETDADPHNARRGFFFSHIGWLFVRKHRDVIEKGRKLDVTDLLADPVVRIQRKYYKISVVLMCFVVPTLVPWYIWGESLWNSYFLASILRYTISLNISWLVNSAAHMYGNRPYDKHISPRQNPLVALGAIGEGFHNYHHTFPFDYSASEFGLNFNPTTWFIDFMCWLGLATDRKRATKPMIEARKARTGDSSA
  
Inhibitor
Name:
BDBM50329986
Synonyms:
6-tert-butyl-2-(2'-fluorobiphenyl-4-yl)-1H-benzo[d]imidazole | CHEMBL1272145
Type:
Small organic molecule
Emp. Form.:
C23H21FN2
Mol. Mass.:
344.4246
SMILES:
CC(C)(C)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F
Structure:
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