Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50299697
Substrate
n/a
Meas. Tech.
ChEMBL_685335 (CHEMBL1287450)
Ki
0.398107±n/a nM
Citation
 Dal Ben, D; Buccioni, M; Lambertucci, C; Marucci, G; Thomas, A; Volpini, R; Cristalli, G Molecular modeling study on potent and selective adenosine A(3) receptor agonists. Bioorg Med Chem 18:7923-30 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50299697
Synonyms:
2-(2-Pyridinyl)ethynyl-N6-methyl-5'-N-methylcarboxamidoadenosine | CHEMBL575027
Type:
Small organic molecule
Emp. Form.:
C19H19N7O4
Mol. Mass.:
409.3987
SMILES:
CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC)nc(nc12)C#Cc1ccccn1 |r|
Structure:
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