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TargetChymase
LigandBDBM50332960
Substrate/Competitorn/a
Meas. Tech.ChEMBL_696202
IC50 3.1±n/a nM
Citation Mehta, PDSengar, NPPathak, AK 2-Azetidinone--a new profile of various pharmacological activities. Eur J Med Chem45:5541-60 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Chymase
Name:Chymase
Synonyms:Alpha-chymase | Chymase precursor | Mast cell protease I
Type:Enzyme
Mol. Mass.:27340.12
Organism:Homo sapiens (Human)
Description:n/a
Residue:247
Sequence:
MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNF
VLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKA
SLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD
FDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWI
NQILQAN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50332960
NameBDBM50332960
Synonyms:(3S,4S)-4-(4-Carboxy)phenoxy-1-[diphenylmethyl)aminocarbonyl]-3-(2-ethoxybenzyl)azetidin-2-one | CHEMBL1631756
TypeSmall organic molecule
Emp. Form.C33H30N2O6
Mol. Mass.550.6011
SMILESCCOc1ccccc1C[C@H]1[C@@H](Oc2ccc(cc2)C(O)=O)N(C(=O)NC(c2ccccc2)c2ccccc2)C1=O |r|
Structure
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n/a