Reaction Details Report a problem with these data
Target
Carbonic anhydrase
Ligand
BDBM10869
Substrate
n/a
Meas. Tech.
ChEMBL_700658 (CHEMBL1645697)
Ki
91.9±n/a nM
Citation
 Bertucci, A; Innocenti, A; Scozzafava, A; Tambutté, S; Zoccola, D; Supuran, CT Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. Bioorg Med Chem Lett 21:710-4 (2011) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
Alpha carbonic anhydrase
Type:
PROTEIN
Mol. Mass.:
36650.57
Organism:
Stylophora pistillata
Description:
ChEMBL_700658
Residue:
323
Sequence:
MKLSLFISSLLAMIVACPNLAESAGSWTYRDPEGPDTWKHHYKDCEGHEQSPINIVPKDTFFEPGLADLVVNYEKSVSAKLFNNGHTVQATFLTGKSNISGGNLTSHFRALQMHFHWGSENSRGSEHQVGGRKFPLEIHIVHYNAEKYPSVSEAVDKGDGLAVLGILVELQVQDNPVFDVMVDNLDKARYKGNEVILPSLQPFSFLPHDIAQYYTYRGSLTTPGCFESVQWFVFNHTFPISQAQLDKFRDLFDSEKQDTKKLPLVDNYRPVQPLYGRSVSEASNALLFPVARHQTKLWIAWDSLMTRQYFMKQQSICALYQPQ
  
Inhibitor
Name:
BDBM10869
Synonyms:
5-imino-4-methyl-4,5-dihydro-1,3,4-thiadiazole-2-sulfonamide | CHEMBL6753 | aromatic/heteroaromatic sulfonamide 14
Type:
Small organic molecule
Emp. Form.:
C3H6N4O2S2
Mol. Mass.:
194.235
SMILES:
Cn1nc(sc1=N)S(N)(=O)=O
Structure:
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