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Target
Beta-lactamase
Ligand
BDBM50240480
Substrate
n/a
Meas. Tech.
ChEMBL_715807 (CHEMBL1663882)
Ki
7±n/a nM
Citation
 Rodríguez-Martínez, JM; Nordmann, P; Ronco, E; Poirel, L Extended-spectrum cephalosporinase in Acinetobacter baumannii. Antimicrob Agents Chemother 54:3484-8 (2010) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase ADC-33
Type:
PROTEIN
Mol. Mass.:
40551.94
Organism:
Acinetobacter baumannii
Description:
ChEMBL_715812
Residue:
359
Sequence:
LFIFNTSIYAGNTPKDQEIKKLVDQNFKPLLEKYDVPGMAVGVIQNNKKYEMYYGLQSVQDKKAVNSSTIFELGSVSKLFTATAGAYAKNKGKISFDDTPGKYWKELKNTPIDQVNLLQLATYTSGNLALQFPDEVQTDQQVLTFFKDWKPKNPIGEYRQYSNPSIGLFGKVVALSMNKPFDQVLEKIIFPALGLKHSYVNVAKTQMQNYAFGYNQENQPIRVNPGPLDAPAYGVKSTLPDMLSFIHANLNPQKYPADIQRAINETHQGRYQVNTMYQALGWEEFSYPATLQTLLDSNSEQIVMKPNKVTAISKEPSVKMYHKTGSTNGFGTYVVFIPKENIGLVMLTNKRIPNEERIK
  
Inhibitor
Name:
BDBM50240480
Synonyms:
(2S,3S)-3-({(2Z)-2-(2-ammonio-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]ethanoyl}amino)-2-methyl-4-oxoazetidine-1-sulfonate | (2S,3S)-3-({(2Z)-2-(2-ammonio-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]ethanoyl}amino)-2-methyl-4-oxoazetidine-1-sulfonate(aztreonam) | 2-[1-(2-Amino-thiazol-4-yl)-1-((2S,3S)-2-methyl-4-oxo-1-sulfo-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-2-methyl-propionic acid | AZTREONAM | Azactam | Azetreonam | CHEMBL158 | SQ-26776
Type:
Small organic molecule
Emp. Form.:
C13H17N5O8S2
Mol. Mass.:
435.433
SMILES:
C[C@H]1[C@H](NC(=O)C(=N/OC(C)(C)C(O)=O)\c2csc(N)n2)C(=O)N1S(O)(=O)=O |r|
Structure:
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