Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50335712
Substrate
n/a
Meas. Tech.
ChEMBL_715074 (CHEMBL1664180)
Ki
3.6±n/a nM
Citation
 Yaziji, V; Rodríguez, D; Gutiérrez-de-Terán, H; Coelho, A; Caamaño, O; García-Mera, X; Brea, J; Loza, MI; Cadavid, MI; Sotelo, E Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists. J Med Chem 54:457-71 (2011) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50335712
Synonyms:
CHEMBL1650356 | N-2,6-bis4-methoxyphenyl)pyrimidin-4-yl)propionamide
Type:
Small organic molecule
Emp. Form.:
C21H21N3O3
Mol. Mass.:
363.4097
SMILES:
CCC(=O)Nc1cc(nc(n1)-c1ccc(OC)cc1)-c1ccc(OC)cc1
Structure:
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