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TargetAngiotensin II receptor
LigandBDBM50335930
Substrate/Competitorn/a
Meas. Tech.ChEMBL_717444
Ki 10±n/a nM
Citation Naik, PMurumkar, PGiridhar, RYadav, MR Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorg Med Chem18:8418-56 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Angiotensin II receptor
Name:Angiotensin II receptor
Synonyms:AT1 | AT1AR | AT1BR | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1)
Type:Protein
Mol. Mass.:41080.75
Organism:Homo sapiens (Human)
Description:P30556
Residue:359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50335930
NameBDBM50335930
Synonyms:CHEMBL1668000 | N-(4'-((3-butyl-6,9-dioxo-2,3-diazaspiro[4.4]nonan-2-yl)methyl)biphenyl-2-ylsulfonyl)benzamide
TypeSmall organic molecule
Emp. Form.C31H33N3O5S
Mol. Mass.559.676
SMILESCCCCN1CC2(CN1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1)C(=O)CCC2=O
Structure
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