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Target
Polyphenol oxidase 2
Ligand
BDBM50336361
Substrate
n/a
Meas. Tech.
ChEMBL_716753 (CHEMBL1670635)
IC50
4690±n/a nM
Citation
 Fang, Y; Chen, Y; Feng, G; Ma, L Benzyl benzoates: New phlorizin analogs as mushroom tyrosinase inhibitors. Bioorg Med Chem 19:1167-71 (2011) [PubMed]  Article 
Target
Name:
Polyphenol oxidase 2
Synonyms:
Monophenol monooxygenase | Monophenol oxidase | PPO2 | PPO2_AGABI | Tyrosinase
Type:
Protein
Mol. Mass.:
63923.66
Organism:
Agaricus bisporus (Common mushroom)
Description:
O42713
Residue:
556
Sequence:
MSLIATVGPTGGVKNRLNIVDFVKNEKFFTLYVRSLELLQAKEQHDYSSFFQLAGIHGLPFTEWAKERPSMNLYKAGYCTHGQVLFPTWHRTYLSVLEQILQGAAIEVAKKFTSNQTDWVQAAQDLRQPYWDWGFELMPPDEVIKNEEVNITNYDGKKISVKNPILRYHFHPIDPSFKPYGDFATWRTTVRNPDRNRREDIPGLIKKMRLEEGQIREKTYNMLKFNDAWERFSNHGISDDQHANSLESVHDDIHVMVGYGKIEGHMDHPFFAAFDPIFWLHHTNVDRLLSLWKAINPDVWVTSGRNRDGTMGIAPNAQINSETPLEPFYQSGDKVWTSASLADTARLGYSYPDFDKLVGGTKELIRDAIDDLIDERYGSKPSSGARNTAFDLLADFKGITKEHKEDLKMYDWTIHVAFKKFELKESFSLLFYFASDGGDYDQENCFVGSINAFRGTAPETCANCQDNENLIQEGFIHLNHYLARDLESFEPQDVHKFLKEKGLSYKLYSRGDKPLTSLSVKIEGRPLHLPPGEHRPKYDHTQARVVFDDVAVHVIN
  
Inhibitor
Name:
BDBM50336361
Synonyms:
4-Hydroxybenzyl 2,4-dihydroxybenzoate | CHEMBL1668051
Type:
Small organic molecule
Emp. Form.:
C14H12O5
Mol. Mass.:
260.2421
SMILES:
Oc1ccc(COC(=O)c2ccc(O)cc2O)cc1
Structure:
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