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Target
Delta-type opioid receptor
Ligand
BDBM50336603
Substrate
n/a
Meas. Tech.
ChEMBL_725831 (CHEMBL1678427)
Ki
200±n/a nM
Citation
 Cheng, K; Lee, YS; Rothman, RB; Dersch, CM; Bittman, RW; Jacobson, AE; Rice, KC Probes for narcotic receptor mediated phenomena. 41. Unusual inverseµ-agonists and potentµ-opioid antagonists by modification of the N-substituent in enantiomeric 5-(3-hydroxyphenyl)morphans. J Med Chem 54:957-69 (2011) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50336603
Synonyms:
3-((1R,5S)-2-(((1'R,2'R)-2-Phenylcyclopropyl)methyl)-2-azabicyclo[3.3.1]nonan-5-yl)phenol hydrochloride | CHEMBL1672184
Type:
Small organic molecule
Emp. Form.:
C24H29NO
Mol. Mass.:
347.4932
SMILES:
Oc1cccc(c1)[C@@]12CCC[C@@H](C1)N(C[C@@H]1C[C@H]1c1ccccc1)CC2 |r|
Structure:
Search PDB for entries with ligand similarity: