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TargetAdrenergic beta-2 receptor (beta2)
LigandBDBM25771
Substrate/Competitorn/a
Meas. Tech.ChEMBL_726948
Ki 2.4±n/a nM
Citation Hughes, ADChin, KHDunham, SLJasper, JRKing, KELee, TWMammen, MMartin, JSteinfeld, T Discovery of muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist (MABA) dual pharmacology molecules. Bioorg Med Chem Lett21:1354-8 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adrenergic beta-2 receptor (beta2)
Name:Adrenergic beta-2 receptor (beta2)
Synonyms:ADRB2 | ADRB2R | ADRB2R, B2AR | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:n/a
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM25771
NameBDBM25771
Synonyms:1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]-2-methylol-phenol | 4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol | Aeromax | Salmeterol | Serevent | salmeterol xinafoate
TypeSmall organic molecule
Emp. Form.C25H37NO4
Mol. Mass.415.5656
SMILESOCc1cc(ccc1O)C(O)CNCCCCCCOCCCCc1ccccc1
Structure
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n/a