Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50339684
Substrate
n/a
Meas. Tech.
ChEMBL_735244 (CHEMBL1694506)
Ki
1.1±n/a nM
Citation
 Tu, Z; Li, S; Cui, J; Xu, J; Taylor, M; Ho, D; Luedtke, RR; Mach, RH Synthesis and pharmacological evaluation of fluorine-containing D3 dopamine receptor ligands. J Med Chem 54:1555-64 (2011) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50339684
Synonyms:
4-(2-Fluoroethyl)-N-(4-(4-(2-(2-Fluoroethoxy)phenyl)piperazin-1-yl)-trans-butyl-2-enyl)benzamide oxalic acid salt | CHEMBL1689009
Type:
Small organic molecule
Emp. Form.:
C25H31F2N3O2
Mol. Mass.:
443.5293
SMILES:
FCCOc1ccccc1N1CCN(C\C=C\CNC(=O)c2ccc(CCF)cc2)CC1
Structure:
Search PDB for entries with ligand similarity: