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Target
Beta-lactamase
Ligand
BDBM50339852
Substrate
n/a
Meas. Tech.
ChEMBL_740684 (CHEMBL1763746)
Ki
63220±n/a nM
Citation
 Xia, Y; Cao, K; Zhou, Y; Alley, MR; Rock, F; Mohan, M; Meewan, M; Baker, SJ; Lux, S; Ding, CZ; Jia, G; Kully, M; Plattner, JJ Synthesis and SAR of novel benzoxaboroles as a new class of β-lactamase inhibitors. Bioorg Med Chem Lett 21:2533-6 (2011) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ENTCL | ampC
Type:
PROTEIN
Mol. Mass.:
41306.67
Organism:
Enterobacter cloacae
Description:
ChEMBL_40258
Residue:
381
Sequence:
MMRKSLCCALLLGISCSALATPVSEKQLAEVVANTITPLMKAQSVPGMAVAVIYQGKPHYYTFGKADIAANKPVTPQTLFELGSISKTFTGVLGGDAIARGEISLDDAVTRYWPQLTGKQWQGIRMLDLATYTAGGLPLQVPDEVTDNASLLRFYQNWQPQWKPGTTRLYANASIGLFGALAVKPSGMPYEQAMTTRVLKPLKLDHTWINVPKAEEAHYAWGYRDGKAVRVSPGMLDAQAYGVKTNVQDMANWVMANMAPENVADASLKQGIALAQSRYWRIGSMYQGLGWEMLNWPVEANTVVEGSDSKVALAPLPVAEVNPPAPPVKASWVHKTGSTGGFGSYVAFIPEKQIGIVMLANTSYPNPARVEAAYHILEALQ
  
Inhibitor
Name:
BDBM50339852
Synonyms:
6-(phenylsulfonyl)benzo[c][1,2]oxaborol-1(3H)-ol | CHEMBL1761257
Type:
Small organic molecule
Emp. Form.:
C13H11BO4S
Mol. Mass.:
274.1
SMILES:
OB1OCc2ccc(cc12)S(=O)(=O)c1ccccc1
Structure:
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