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TargetMas-related G-protein coupled receptor member X1
LigandBDBM50340746
Substrate/Competitorn/a
Meas. Tech.ChEMBL_740644
IC50 40±n/a nM
Citation Bayrakdarian, MButterworth, JHu, YJSanthakumar, VTomaszewski, MJ Development of 2,4-diaminopyrimidine derivatives as novel SNSR4 antagonists. Bioorg Med Chem Lett21:2102-5 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mas-related G-protein coupled receptor member X1
Name:Mas-related G-protein coupled receptor member X1
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:36253.68
Organism:Homo sapiens (Human)
Description:ChEMBL_516621
Residue:322
Sequence:
MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNA
FSIYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTER
CLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFIT
VAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFL
WIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASE
VDEGGGQLPEEILELSGSRLEQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50340746
NameBDBM50340746
Synonyms:2-(4-(2-(4-chlorophenethylamino)pyrimidin-4-yl)piperazin-1-yl)-N-(pyridin-4-ylmethyl)-N-((tetrahydrofuran-2-yl)methyl)acetamide | CHEMBL1762701
TypeSmall organic molecule
Emp. Form.C29H36ClN7O2
Mol. Mass.550.095
SMILESClc1ccc(CCNc2nccc(n2)N2CCN(CC(=O)N(CC3CCCO3)Cc3ccncc3)CC2)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a