Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50342006
Substrate
n/a
Meas. Tech.
ChEMBL_743583 (CHEMBL1768083)
Ki
61000±n/a nM
Citation
 Samanta, A; Dasgupta, S; Pathak, T 5'-Modified pyrimidine nucleosides as inhibitors of ribonuclease A. Bioorg Med Chem 19:2478-84 (2011) [PubMed]  Article 
Target
Name:
Ribonuclease pancreatic
Synonyms:
CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1
Type:
Enzyme
Mol. Mass.:
16468.79
Organism:
Bison bison (American bison)
Description:
carboxamidomethylated RNase A
Residue:
150
Sequence:
MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV
  
Inhibitor
Name:
BDBM50342006
Synonyms:
5'-Deoxy-5'-N-(4-carboxypiperidinyl)uridine | CHEMBL1765476
Type:
Small organic molecule
Emp. Form.:
C15H21N3O7
Mol. Mass.:
355.3431
SMILES:
O[C@@H]1[C@@H](CN2CCC(CC2)C(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Structure:
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