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TargetNeurotensin receptor
LigandBDBM50342238
Substrate/Competitorn/a
Meas. Tech.ChEMBL_743647
Ki 0.610000±n/a nM
Citation Einsiedel, JHeld, CHervet, MPlomer, MTschammer, NHübner, HGmeiner, P Discovery of highly potent and neurotensin receptor 2 selective neurotensin mimetics. J Med Chem54:2915-23 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Neurotensin receptor
Name:Neurotensin receptor
Synonyms:Levocabastine-sensitive neurotensin receptor | NT-R-2 | NTR2 | NTR2 receptor | Neurotensin receptor 2 | Neurotensin receptor type 2
Type:PROTEIN
Mol. Mass.:45404.76
Organism:Homo sapiens (Human)
Description:ChEMBL_1281495
Residue:410
Sequence:
METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHVVLKA
RAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAY
ATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKHEL
ETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQV
PSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRRIRSLQRSVQVLR
AIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAVTPLLYNA
VSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQSPTLMDTASGFGDPPETRT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50342238
NameBDBM50342238
Synonyms:(S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-2-((S)-3-amino-6-guanidinohexanamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3-methylpentanamido)-4-methylpentanoic acid | CHEMBL1766935
TypeSmall organic molecule
Emp. Form.C39H66N12O8
Mol. Mass.831.0169
SMILES[#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](-[#8])=O |r|
Structure
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