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TargetAngiotensin II receptor
LigandBDBM50347563
Substrate/Competitorn/a
Meas. Tech.ChEMBL_757051
Ki 0.69±n/a nM
Citation Casimiro-Garcia, AFilzen, GFFlynn, DBigge, CFChen, JDavis, JADudley, DAEdmunds, JJEsmaeil, NGeyer, AHeemstra, RJJalaie, MOhren, JFOstroski, REllis, TSchaum, RPStoner, C Discovery of a series of imidazo[4,5-b]pyridines with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-¿. J Med Chem54:4219-33 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Angiotensin II receptor
Name:Angiotensin II receptor
Synonyms:AT1 | AT1AR | AT1BR | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1)
Type:Protein
Mol. Mass.:41080.75
Organism:Homo sapiens (Human)
Description:P30556
Residue:359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
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  Blast E-value cutoff:
BDBM50347563
NameBDBM50347563
Synonyms:CHEMBL1801740
TypeSmall organic molecule
Emp. Form.C29H31N7
Mol. Mass.477.6033
SMILESCCc1nc2c(C)cc(CC(C)C)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r|
Structure
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