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Target
Beta-2 adrenergic receptor
Ligand
BDBM50213120
Substrate
n/a
Meas. Tech.
ChEMBL_755357 (CHEMBL1804513)
EC50
506±n/a nM
Citation
 Jozwiak, K; Woo, AY; Tanga, MJ; Toll, L; Jimenez, L; Kozocas, JA; Plazinska, A; Xiao, RP; Wainer, IW Comparative molecular field analysis of fenoterol derivatives: A platform towards highly selective and effective beta(2)-adrenergic receptor agonists. Bioorg Med Chem 18:728-36 (2010) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_RAT | Adrb2 | Adrb2r | Adrenergic receptor beta
Type:
PROTEIN
Mol. Mass.:
46896.26
Organism:
Rattus norvegicus
Description:
ChEMBL_38603
Residue:
418
Sequence:
MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQAIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRANLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNGRTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
  
Inhibitor
Name:
BDBM50213120
Synonyms:
(R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydroxyphenyl-beta-oxy)ethylaminopropane | CHEMBL228996 | US10617654, Compound (R,S)-2 | US9249163, 33 | US9492405, (R,S)-2
Type:
Small organic molecule
Emp. Form.:
C18H23NO4
Mol. Mass.:
317.3795
SMILES:
COc1ccc(C[C@H](C)NC[C@H](O)c2cc(O)cc(O)c2)cc1
Structure:
Search PDB for entries with ligand similarity: