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Target
Vitamin D3 receptor
Ligand
BDBM50353860
Substrate
n/a
Meas. Tech.
ChEMBL_769453 (CHEMBL1831393)
Ki
0.3±n/a nM
Citation
 Glebocka, A; Sicinski, RR; Plum, LA; Deluca, HF Synthesis and biological activity of 2-(3'-hydroxypropylidene)-1a-hydroxy-19-norvitamin D analogues with shortened alkyl side chains. J Med Chem 54:6832-42 (2011) [PubMed]  Article 
Target
Name:
Vitamin D3 receptor
Synonyms:
Nr1i1 | VDR_RAT | Vdr | Vitamin D receptor
Type:
PROTEIN
Mol. Mass.:
47811.07
Organism:
Rattus norvegicus
Description:
ChEMBL_1505946
Residue:
423
Sequence:
MEATAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIMKRKEEEALKDSLRPKLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMDGSTGSYSPRPTLSFSGNSSSSSSDLYTTSLDMMEPSGFSNLDLNGEDSDDPSVTLDLSPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGNEIS
  
Inhibitor
Name:
BDBM50353860
Synonyms:
CHEMBL1830164
Type:
Small organic molecule
Emp. Form.:
C26H40O3
Mol. Mass.:
400.594
SMILES:
CC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)\C(=C/CCO)[C@H](O)C1=C |r|
Structure:
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