Target
Acrosin
Ligand
BDBM50354886
Substrate
n/a
Meas. Tech.
ChEMBL_772454 (CHEMBL1839245)
IC50
142600000±n/a nM
Citation
 Qi, JZhu, JLiu, XDing, LZheng, CHan, GLv, JZhou, Y Synthesis and acrosin inhibitory activities of substituted ethyl 5-(4-aminophenyl)-1H-pyrazole-3-carboxylate derivatives. Bioorg Med Chem Lett 21:5822-5 (2011) [PubMed]  Article 
Target
Name:
Acrosin
Synonyms:
ACR | ACRO_HUMAN | ACRS
Type:
PROTEIN
Mol. Mass.:
45865.48
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1365286
Residue:
421
Sequence:
MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASPLPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTSTS
  
Inhibitor
Name:
BDBM50354886
Synonyms:
CHEMBL466465
Type:
Small organic molecule
Emp. Form.:
C14H21ClN2O3S
Mol. Mass.:
332.846
SMILES:
Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl |r|
Structure:
Search PDB for entries with ligand similarity: