Reaction Details Report a problem with these data
Target
UDP-glucuronosyltransferase 2B7
Ligand
BDBM50003616
Substrate
n/a
Meas. Tech.
ChEMBL_774127 (CHEMBL1908132)
Ki
1600000±n/a nM
Citation
 Kiang, TK; Ensom, MH; Chang, TK UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacol Ther 106:97-132 (2005) [PubMed]  Article 
Target
Name:
UDP-glucuronosyltransferase 2B7
Synonyms:
2.4.1.17 | 3,4-catechol estrogen-specific UDPGT | UD2B7_HUMAN | UDP-glucuronosyltransferase 2B7 | UDP-glucuronosyltransferase 2B9 | UDPGT 2B7 | UDPGT 2B9 | UDPGTh-2 | UGT2B7 | UGTB2B9 | Uridine-5'-diphosphoglucuronosyltransferase 2B7
Type:
Enzyme
Mol. Mass.:
60705.98
Organism:
Homo sapiens (Human)
Description:
P16662
Residue:
529
Sequence:
MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFWLYFSQVQEIMSIFGDITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTFEKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVLGRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQSSGENGVVVFSLGSMVSNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGKND
  
Inhibitor
Name:
BDBM50003616
Synonyms:
2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n-propylessigsaeure | VALPROIC ACID | Valproinsaeure | dipropylacetic acid | n-DPA
Type:
Small organic molecule
Emp. Form.:
C8H16O2
Mol. Mass.:
144.2114
SMILES:
CCCC(CCC)C(O)=O
Structure:
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