Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50356549
Substrate
n/a
Meas. Tech.
ChEMBL_776031 (CHEMBL1912501)
Ki
161.7±n/a nM
Citation
 Piscitelli, F; Ligresti, A; La Regina, G; Gatti, V; Brizzi, A; Pasquini, S; Allarà, M; Carai, MA; Novellino, E; Colombo, G; Di Marzo, V; Corelli, F; Silvestri, R 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: an effective scaffold for the design of either CB1 or CB2 receptor ligands. Eur J Med Chem 46:5641-53 (2011) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50356549
Synonyms:
CHEMBL1909857
Type:
Small organic molecule
Emp. Form.:
C22H14Cl6N4O
Mol. Mass.:
563.091
SMILES:
Cc1c(nn(c1-n1c(Cl)ccc1Cl)-c1ccc(Cl)c(Cl)c1)C(=O)NCc1ccc(Cl)c(Cl)c1 |(18.71,-36.55,;19.62,-37.8,;21.16,-37.8,;21.63,-39.27,;20.38,-40.17,;19.14,-39.26,;17.67,-39.72,;16.43,-38.79,;16.46,-37.24,;15.17,-39.67,;15.63,-41.15,;17.17,-41.17,;18.05,-42.43,;20.38,-41.71,;19.04,-42.47,;19.04,-44.01,;20.37,-44.79,;20.37,-46.33,;21.71,-44.01,;23.05,-44.78,;21.71,-42.47,;22.06,-36.56,;21.44,-35.15,;23.6,-36.72,;24.5,-35.47,;26.04,-35.46,;26.82,-36.78,;28.35,-36.77,;29.11,-35.43,;30.65,-35.41,;28.32,-34.1,;29.07,-32.76,;26.79,-34.12,)|
Structure:
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