Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetProton-coupled amino acid transporter 1
LigandBDBM50357233
Substrate/Competitorn/a
Meas. Tech.ChEMBL_788189
Ki 9000000±n/a nM
Citation Thondorf, IVoigt, VSchäfer, SGebauer, SZebisch, KLaug, LBrandsch, M Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1). Bioorg Med Chem19:6409-18 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Proton-coupled amino acid transporter 1
Name:Proton-coupled amino acid transporter 1
Synonyms:Proton/amino acid transporter 1 | Solute carrier family 36 member 1 | hPAT1
Type:PROTEIN
Mol. Mass.:53078.06
Organism:Homo sapiens (Human)
Description:ChEMBL_788189
Residue:476
Sequence:
MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN
IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV
MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC
HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV
QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT
ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP
FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE
VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50357233
NameBDBM50357233
Synonyms:CHEMBL352418
TypeSmall organic molecule
Emp. Form.C5H9NO3
Mol. Mass.131.1299
SMILESO[C@H]1CN[C@@H](C1)C(O)=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a