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Target
Luciferin 4-monooxygenase
Ligand
BDBM50357676
Substrate
n/a
Meas. Tech.
ChEMBL_786225 (CHEMBL1920146)
EC50
730±n/a nM
Citation
 Somanadhan, B; Leong, C; Whitton, SR; Ng, S; Buss, AD; Butler, MS Identification of a naturally occurring quinazolin-4(3H)-one firefly luciferase inhibitor. J Nat Prod 74:1500-2 (2011) [PubMed]  Article 
Target
Name:
Luciferin 4-monooxygenase
Synonyms:
LUCI_AQULA | Luciferase
Type:
PROTEIN
Mol. Mass.:
60126.66
Organism:
Luciola lateralis
Description:
ChEMBL_786225
Residue:
548
Sequence:
MENMENDENIVYGPEPFYPIEEGSAGAQLRKYMDRYAKLGAIAFTNALTGVDYTYAEYLEKSCCLGEALKNYGLVVDGRIALCSENCEEFFIPVLAGLFIGVGVAPTNEIYTLRELVHSLGISKPTIVFSSKKGLDKVITVQKTVTAIKTIVILDSKVDYRGYQSMDNFIKKNTPQGFKGSSFKTVEVNRKEQVALIMNSSGSTGLPKGVQLTHENAVTRFSHARDPIYGNQVSPGTAILTVVPFHHGFGMFTTLGYLTCGFRIVMLTKFDEETFLKTLQDYKCSSVILVPTLFAILNRSELLDKYDLSNLVEIASGGAPLSKEIGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKPGASGKVVPLFKAKVIDLDTKKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDEEGWLHTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPIAGELPGAVVVLEKGKSMTEKEVMDYVASQVSNAKRLRGGVRFVDEVPKGLTGKIDGKAIREILKKPVAKM
  
Inhibitor
Name:
BDBM50357676
Synonyms:
CHEMBL1914948
Type:
Small organic molecule
Emp. Form.:
C15H13N3O
Mol. Mass.:
251.2832
SMILES:
CNc1ccc(cc1)-c1nc2ccccc2c(=O)[nH]1
Structure:
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