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Reaction Details
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TargetTrace amine-associated receptor 1 (TAAR1)
LigandBDBM50022723
Substrate/Competitorn/a
Meas. Tech.ChEMBL_792739
EC50 1200±n/a nM
Citation Lewin, AHMiller, GMGilmour, B Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class. Bioorg Med Chem19:7044-8 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Trace amine-associated receptor 1 (TAAR1)
Name:Trace amine-associated receptor 1
Synonyms:Trace amine receptor 1 (TARR1) | Trace amine-associated receptor1
Type:Enzyme
Mol. Mass.:38034.73
Organism:Rattus norvegicus (Rat)
Description:Q923Y9
Residue:332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWL
LHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDR
YYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRG
CFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQ
SKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMV
YAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
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BDBM50022723
NameBDBM50022723
Synonyms:(+)-(S)-amphetamine | (+)-alpha-methylphenethylamine | (+)-alpha-methylphenylethylamine | (2S)-1-phenylpropan-2-amine | (S)-(+)-amphetamine | (S)-(+)-beta-phenylisopropylamine | (S)-1-phenyl-2-aminopropane | (S)-1-phenyl-2-propylamine | (S)-alpha-methylbenzeneethanamine | (S)-amphetamine | (alphaS)-alpha-methylbenzeneethanamine | CHEMBL612 | DEXTROAMPHETAMINE | Dextroamphetamine | d-amphetamine | dexamphetamine
TypeSmall organic molecule
Emp. Form.C9H13N
Mol. Mass.135.2062
SMILESC[C@H](N)Cc1ccccc1 |r|
Structure
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n/a