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Target
Casein kinase II subunit alpha'
Ligand
BDBM50156669
Substrate
n/a
Meas. Tech.
ChEMBL_792165 (CHEMBL1930612)
Ki
343±n/a nM
Citation
 Janeczko, M; Orzeszko, A; Kazimierczuk, Z; Szyszka, R; Baier, A CK2a and CK2a' subunits differ in their sensitivity to 4,5,6,7-tetrabromo- and 4,5,6,7-tetraiodo-1H-benzimidazole derivatives. Eur J Med Chem 47:345-50 (2012) [PubMed]  Article 
Target
Name:
Casein kinase II subunit alpha'
Synonyms:
CK2A2 | CSK22_HUMAN | CSNK2A2 | Casein kinase II alpha (prime) | Casein kinase II alpha' | Casein kinase II subunit alpha (CK2A2) | Casein kinase II subunit alpha (CSNK2A2)
Type:
Protein
Mol. Mass.:
41223.82
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
350
Sequence:
MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
  
Inhibitor
Name:
BDBM50156669
Synonyms:
4,5,6,7-TETRABROMO-BENZIMIDAZOLE | 4,5,6,7-tetrabromo-1H-benzimidazole | 4,5,6,7-tetrabromo-1H-benzo[d]imidazole | 4,5,6,7-tetrabromo-1Hbenzimidazole (1) | 4,5,6,7-tetrabromobenzimidazole | CHEMBL373937
Type:
Small organic molecule
Emp. Form.:
C7H2Br4N2
Mol. Mass.:
433.72
SMILES:
Brc1c(Br)c(Br)c2[nH]cnc2c1Br
Structure:
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