Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM50360142
Substrate
n/a
Meas. Tech.
ChEMBL_793549 (CHEMBL1932300)
EC50
0.190000±n/a nM
Citation
 Ida, Y; Nemoto, T; Hirayama, S; Fujii, H; Osa, Y; Imai, M; Nakamura, T; Kanemasa, T; Kato, A; Nagase, H Synthesis of quinolinomorphinan-4-ol derivatives asd opioid receptor agonists. Bioorg Med Chem 20:949-61 (2012) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50360142
Synonyms:
CHEMBL1929365
Type:
Small organic molecule
Emp. Form.:
C27H28N2O
Mol. Mass.:
396.524
SMILES:
Oc1cccc2C[C@@H]3[C@@H]4Cc5cc6ccccc6nc5C[C@]4(CCN3CC3CC3)c12 |r,THB:25:24:8:29.5.6|
Structure:
Search PDB for entries with ligand similarity: