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Target
Adenosine 5'-monophosphoramidase HINT1
Ligand
BDBM50360477
Substrate
n/a
Meas. Tech.
ChEMBL_795618 (CHEMBL1936048)
Ki
457000±n/a nM
Citation
 Bardaweel, SK; Ghosh, B; Wagner, CR Synthesis and evaluation of potential inhibitors of human and Escherichia coli histidine triad nucleotide binding proteins. Bioorg Med Chem Lett 22:558-60 (2011) [PubMed]  Article 
Target
Name:
Adenosine 5'-monophosphoramidase HINT1
Synonyms:
Adenosine 5'-monophosphoramidase | HINT | HINT1 | HINT1_HUMAN | Histidine triad nucleotide-binding protein 1 | PKCI-1 | PKCI1 | PRKCNH1 | Protein kinase C inhibitor 1 | Protein kinase C-interacting protein 1
Type:
PROTEIN
Mol. Mass.:
13803.77
Organism:
Homo sapiens (Human)
Description:
ChEMBL_795618
Residue:
126
Sequence:
MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG
  
Inhibitor
Name:
BDBM50360477
Synonyms:
CHEMBL1934753
Type:
Small organic molecule
Emp. Form.:
C22H24N6O5
Mol. Mass.:
452.4632
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COC(=O)CCCc2c[nH]c3ccccc23)[C@@H](O)[C@H]1O |r|
Structure:
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