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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50132472
Substrate
n/a
Meas. Tech.
ChEMBL_796385 (CHEMBL1937700)
EC50
1920±n/a nM
Citation
 Nomura, M; Yumoto, K; Shinozaki, T; Isogai, S; Takano, Y; Murakami, K Discovery of cyclic amine-substituted benzoic acids as PPARa agonists. Bioorg Med Chem Lett 22:334-8 (2011) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Homo sapiens (Human)
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50132472
Synonyms:
(S)-2-{3-[4-(4-Fluoro-phenoxy)-benzylcarbamoyl]-4-methoxy-benzyl}-butyric acid | CHEMBL318351
Type:
Small organic molecule
Emp. Form.:
C26H26FNO5
Mol. Mass.:
451.4867
SMILES:
CC[C@@H](Cc1ccc(OC)c(c1)C(=O)NCc1ccc(Oc2ccc(F)cc2)cc1)C(O)=O
Structure:
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